![]() fda.gov/news-events/press-announcements/fda-alerts-patients-and-health-care-professionals-nitrosamine-impurity-findings-certain-metformin FDA alerts patients and health care professionals to nitrosamine impurity findings in certain metformin extended-release products.about-cancer/treatment/side-effects/appetite-loss Long-term weight loss with metformin or lifestyle intervention in the diabetes prevention program outcomes study. nhs.uk/medicines/metformin/about-metformin/ You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Learn more about Adderall and weight loss here. Other drugs that may cause weight loss as a side effect include some attention deficit hyperactivity disorder drugs, such as amphetamine/dextroamphetamine (Adderall) and methylphenidate (Concerta). ![]() These drugs include levothyroxine, liothyronine, and liotrix. Taking medications to treat this may cause weight loss as hormones rebalance. One symptom of an underactive thyroid is weight gain. For example, chemotherapy drugs may do this by reducing your appetite.Ĭertain thyroid medications boost your metabolism, which can cause weight loss. Other medications may also cause weight loss. chronic obstructive pulmonary disease (COPD).Some health conditions may also cause loss of appetite, which can lead to weight loss. infections of the stomach or intestines.Digestive issuesĭigestive system issues may also cause weight loss. Weight loss can result from other factors as well. If you’re losing weight while taking metformin, it may or may not be the result of the medication. And even while taking the drug, you may slowly gain back any weight you’ve lost. That means if you stop taking metformin, there’s a good chance you’ll return to your original weight. In addition, any weight loss you have may only last as long as you take the medication. Individuals who follow a healthy diet and exercise while taking metformin tend to lose the most weight. However, taking the drug without following other healthy habits may not lead to weight loss. Researchers found that in people who lost more than 5% of body weight in the first year, those taking metformin had greater success with maintaining weight loss in years 6 to 15. One long-term study of people with diabetes assessed weight loss over 15 years. ![]() These side effects may reduce how much a person wishes to eat. ![]() Some people who take metformin may also experience diarrhea, bloating, and nausea. Metformin may interfere with the gut microbiota, prompt the release of appetite-suppressing hormones, and affect appetite-regulating parts of the brain. However, the methods by which metformin affects appetite aren’t clear. One theory is that metformin prompts you to eat less by reducing your appetite. Unlike other diabetes medications, metformin doesn’t cause weight gain. However, people using metformin for other means may lose weight as a side effect. The FDA doesn’t approve metformin as a stand-alone weight loss drug. ![]()
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